Journal Article

Accuracy of ultrasonographic transcerebellar diameter for dating in third trimester of pregnancy in Nigerian women: a cross-sectional study

Babah, Ochuwa Adiketu, Ofoegbu, Okechukwu Uche, Kusamotu, Olaniyi Araotan, Saalu, Tersur Terry, Maduagu, Charity Opeoluwapo, Irurhe, Nicholas, Familusi, Oluwaseun Emmanuel, Tietie, Lucky Enajite

2025

Overview

Background Accurate prediction of foetal gestational age is of critical importance as it can positively affect the outcome of pregnancy. Routine sonographic estimation of gestational age using biparietal diameter, head circumference, abdominal circumference and femur length is popular but has limitations especially when used as a singly or in late pregnancy. Often pregnant women in low-middle-income countries like Nigeria register for antenatal care late in pregnancy, necessitating the need for a single, cost-effective parameter that requires minimal skills to measure gestational age accurately in late pregnancies. This study examined the accuracy of ultrasonographic transcerebellar diameter compared to other foetal biometric parameters for dating in third trimester of pregnancy. Methodology An analytic cross-sectional study conducted at Lagos University Teaching Hospital, Idi-Araba, Lagos, on 110 pregnant women in their third trimester. Data was collected using an interviewer administered questionnaire. Transabdominal ultrasound scan was done to determine the gestational age by measuring the biparietal diameter, head circumference, abdominal circumference, femur length and transcerebellar diameter. Spearman’s correlation coefficient was used to determine the correlation between the biometric measurements; Accuracy was determine using gestational age from menstrual date as gold standard and comparisons made using Chi square test. Results Mean age of participants was 31.5 ± 5.8 years; mean gestational age 236 ± 25 days. Compared to biparietal diameter, head circumference, abdominal circumference, and femur length, transcerebellar diameter correlates best with gestational age ( r  = 0.8837, p  < 0.001). At an error margin of ± 2weeks, transcerebellar diameter had a high predictive accuracy of 84.6%, though significantly less than that for abdominal circumference alone, 86.4% ( p  = 0.003), and also less than that for all four well known foetal biometric parameters (biparietal diameter, head circumference, abdominal circumference, and femur length) combined, 85.5% ( p  < 0.001). Conclusion Transcerebellar diameter has a better correlation with gestational age than other routine foetal biometric parameters and has high predictive accuracy for dating in third trimester of pregnancy. It may thus play a relevant role in low resource settings where there is shortage of staff and limited skills in obstetric ultrasonography. Clinical trial number Not applicable for this study.

• Publisher: BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
• Subject: Abdominal circumference / Accuracy / Adult / Age / Age determination / Biometrics / Body measurements / Cerebellum - diagnostic imaging / Chi-square test / Circumferences / Comparative analysis / Correlation coefficient / Correlation coefficients / Cross-Sectional Studies / Data collection / Dating / Diameters / Female / Femur / Femur length / Gestational Age / Head circumference / Humans / Imaging / Medical imaging for fetal diseases / Medicine / Medicine & Public Health / Menstruation / Nigeria / Obstetrics / Parameters / Pregnancy / Pregnancy complications / Pregnancy Trimester, Third / Pregnant women / Premature birth / Prenatal care / Radiology / Reproducibility of Results / Sample size / Skills / Transcerebellar diameter / Ultrasonic imaging / Ultrasonography, Prenatal - methods / Ultrasound imaging / Ultrasound scan / Women / Young Adult