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The life-cycle of Toxoplasma gondii reviewed using animations
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Journal Article
The life-cycle of Toxoplasma gondii reviewed using animations
2020
Overview
Toxoplasma gondii
is a protozoan parasite that is the causative agent of toxoplasmosis, an infection with high prevalence worldwide. Most of the infected individuals are either asymptomatic or have mild symptoms, but
T. gondii
can cause severe neurologic damage and even death of the fetus when acquired during pregnancy. It is also a serious condition in immunodeficient patients. The life-cycle of
T. gondii
is complex, with more than one infective form and several transmission pathways. In two animated videos, we describe the main aspects of this cycle, raising questions about poorly or unknown issues of
T. gondii
biology. Original plates, based on electron microscope observations, are also available for teachers, students and researchers. The main goal of this review is to provide a source of learning on the fundamental aspects of
T. gondii
biology to students and teachers contributing for better knowledge and control on this important parasite, and unique cell model. In addition, drawings and videos point to still unclear aspects of
T. gondii
lytic cycle that may stimulate further studies.
Graphical Abstract
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V
Subject
