Asset Details
Do you wish to reserve the book?
Distal radial access to prevent radial artery occlusion for STEMI patients (RAPID III): a randomized controlled trial
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Distal radial access to prevent radial artery occlusion for STEMI patients (RAPID III): a randomized controlled trial
Do you wish to request the book?
Distal radial access to prevent radial artery occlusion for STEMI patients (RAPID III): a randomized controlled trial
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Distal radial access to prevent radial artery occlusion for STEMI patients (RAPID III): a randomized controlled trial
2025
Overview
Background
Compared with conventional transradial access (TRA), distal radial access (DRA) is rarely used for percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI) and may be beneficial to prevent radial artery occlusion (RAO). We aimed to evaluate the incidence of RAO between DRA and TRA 24 h after primary PCI in patients with STEMI.
Methods
This is a single-center, open-label, prospective, randomized controlled trial conducted at Beijing Luhe Hospital, China, between January 2022 and July 2023. Five hundred and twenty patients (mean age: 61.3 ± 13.0 years; 81% male) with STEMI were randomly assigned to the DRA (
n
= 260) or TRA (
n
= 260) group. Primary PCI was performed using the radial artery access assigned study group. The primary endpoint was the rate of RAO assessed using Doppler ultrasound 24 h after primary PCI. Secondary outcomes included time taken for sheath insertion, access success rate, hemostasis time, fluoroscopy time, radiation dosage, and access-related complications.
Results
The incidence of RAO was significantly lower in the DRA group than that in the TRA group (1.9% vs. 8.5%,
P
= 0.001). Access was successful in 94.6% of patients, and the crossover rate was 5.4% in both groups. The median time taken for sheath insertion was significantly longer (133 s vs. 114 s,
P
= 0.009), whereas the mean hemostasis time was shorter (209 ± 71 min vs. 372 ± 70 min,
P
< 0.001) in the DRA group. The incidence of modified Early Discharge After Transradial Stenting of Coronary Arteries (mEASY) ≥ II hematoma was lower in the DRA group (0.8% vs. 3.5%,
P
= 0.033). However, there was no significant difference in fluoroscopy time, radiation dosage, or access-related complications.
Conclusions
In patients with STEMI undergoing primary PCI, compared with TRA, DRA prevented RAO 24 h postoperatively and was associated with shorter hemostasis time and a lower incidence of mEASY ≥ II hematoma.
Trial registration
Clinical Trials.gov Identifier: NCT05461781.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Arterial Occlusive Diseases - epidemiology
/ Arterial Occlusive Diseases - etiology
/ Arterial Occlusive Diseases - prevention & control
/ Dosage
/ Female
/ Hematoma
/ Humans
/ Male
/ Medicine
/ Methods
/ Patients
/ Percutaneous coronary intervention
/ Percutaneous Coronary Intervention - adverse effects
/ Percutaneous Coronary Intervention - methods
/ Sheaths
/ Software
/ ST Elevation Myocardial Infarction - surgery
/ ST-segment elevation myocardial infarction
/ Testing
