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Rapid bacterial identification through volatile organic compound analysis and deep learning
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Rapid bacterial identification through volatile organic compound analysis and deep learning
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Journal Article
Rapid bacterial identification through volatile organic compound analysis and deep learning
2024
Overview
Background
The increasing antimicrobial resistance caused by the improper use of antibiotics poses a significant challenge to humanity. Rapid and accurate identification of microbial species in clinical settings is crucial for precise medication and reducing the development of antimicrobial resistance. This study aimed to explore a method for automatic identification of bacteria using Volatile Organic Compounds (VOCs) analysis and deep learning algorithms.
Results
AlexNet, where augmentation is applied, produces the best results. The average accuracy rate for single bacterial culture classification reached 99.24% using cross-validation, and the accuracy rates for identifying the three bacteria in randomly mixed cultures were SA:98.6%, EC:98.58% and PA:98.99%, respectively.
Conclusion
This work provides a new approach to quickly identify bacterial microorganisms. Using this method can automatically identify bacteria in GC-IMS detection results, helping clinical doctors quickly detect bacterial species, accurately prescribe medication, thereby controlling epidemics, and minimizing the negative impact of bacterial resistance on society.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
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