Asset Details
Do you wish to reserve the book?
Improved Working Memory Performance through Self-Regulation of Dorsal Lateral Prefrontal Cortex Activation Using Real-Time fMRI
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Improved Working Memory Performance through Self-Regulation of Dorsal Lateral Prefrontal Cortex Activation Using Real-Time fMRI
Do you wish to request the book?
Improved Working Memory Performance through Self-Regulation of Dorsal Lateral Prefrontal Cortex Activation Using Real-Time fMRI
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Improved Working Memory Performance through Self-Regulation of Dorsal Lateral Prefrontal Cortex Activation Using Real-Time fMRI
2013
Overview
Working memory is important for a wide range of high-level cognitive activities. Previous studies have shown that the dorsal lateral prefrontal cortex (DLPFC) plays a critical role in working memory and that behavioral training of working memory can alter the activity of DLPFC. However, it is unclear whether the activation in the DLPFC can be self-regulated and whether any self-regulation can affect working memory behavior. The recently emerged real-time functional magnetic resonance imaging (rtfMRI) technique enables the individuals to acquire self-control of localized brain activation, potentially inducing desirable behavioral changes. In the present study, we employed the rtfMRI technique to train subjects to up-regulate the activation in the left DLPFC, which is linked to verbal working memory. After two rtfMRI training sessions, activation in the left DLPFC was significantly increased, whereas the control group that received sham feedback did not show any increase in DLPFC activation. Pre- and post-training behavioral tests indicated that performance of the digit span and letter memory task was significantly improved in the experimental group. Between-group comparison of behavioral changes showed that the increase of digit span in the experimental group was significantly greater than that in the control group. These findings provide preliminary evidence that working memory performance can be improved through learned regulation of activation in associated brain regions using rtfMRI.
Publisher
Public Library of Science,Public Library of Science (PLoS)
Subject
/ Adult
/ Attention deficit hyperactivity disorder
/ Behavior
/ Brain
/ Control
/ Cortex
/ Feedback
/ Female
/ Functional magnetic resonance imaging
/ Groups
/ Humans
/ Language
/ Learning
/ Male
/ Memory
/ Memory, Short-Term - physiology
/ NMR
/ Prefrontal Cortex - diagnostic imaging
/ Prefrontal Cortex - physiology
/ Studies
/ Training
