Asset Details
Do you wish to reserve the book?
Novel insights into immune stress markers associated with myxosporeans gill infection in Nile tilapia (molecular and immunohistochemical studies)
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Novel insights into immune stress markers associated with myxosporeans gill infection in Nile tilapia (molecular and immunohistochemical studies)
Do you wish to request the book?
Novel insights into immune stress markers associated with myxosporeans gill infection in Nile tilapia (molecular and immunohistochemical studies)
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Novel insights into immune stress markers associated with myxosporeans gill infection in Nile tilapia (molecular and immunohistochemical studies)
2024
Overview
Nile tilapia ( Oreochromis niloticus ) is valued in aquaculture because of its quick development and ability to thrive in various environments. Myxosporeans are among the fish parasites that affect fish productivity, as they impact fish growth and reproduction, resulting in large fish deaths in farms and hatcheries. This study has been focused on morpho-molecular identification for the myxosporean parasites infecting Nile tilapia from three governorates in Egypt and assessment of gene expression of different cytokines (Interleukin-1βeta ( IL-1β ), major histocompatibility complex class II ( MHC-II ), and clusters of differentiation 4 ( CD-4 ) and 8 ( CD-8 )) in tissues. Additionally, this work aimed to correlate the developed histopathological alterations and inflammatory reactions in gills with immunohistochemical expression of inducible nitric oxide synthase ( iNOS ) and tumor necrosis factor-alpha ( TNF-α ). Finally, the infected fish’s cortisol levels and blood glucose were assessed. Results of BLAST sequence analysis of the 18S rRNA for the collected protozoans confirmed Myxobolus agolus , M . brachysporus , M . tilapiae , and Henneguya species. The molecular characterization of the immunological status of gills revealed marked upregulation of different inflammatory cytokines in the gills of infected fish. There was a significantly increased serum cortisol and glucose level in infected fish compared with control, non-infected ones. Severe histopathological alterations were observed in the infected fish gills, associated with increased expression of iNOS and TNF-α and related to myxosporean infection. The present study provides new insights into oxidative stress biomarkers in Nile tilapia infected with Myxosporeans and elucidates the gill’s immune status changes as a portal of entry for protozoa that contribute to tissue damage.
Publisher
Public Library of Science
Subject
/ Animals
/ Cortisol
/ Cysts
/ Egypt
/ Ethylenediaminetetraacetic acid
/ Fish
/ Fish Diseases - parasitology
/ Genes
/ Gills
/ Glucose
/ Hormones
/ Major histocompatibility complex
/ Medicine and Health Sciences
/ Nitric Oxide Synthase Type II - genetics
/ Nitric Oxide Synthase Type II - metabolism
/ Parasitic Diseases, Animal - immunology
/ Parasitic Diseases, Animal - parasitology
/ Parasitic Diseases, Animal - pathology
/ Protozoa
/ RNA
/ rRNA 18S
/ Tilapia
