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The role of family factors in antiretroviral therapy (ART) adherence self-efficacy among HIV-infected adolescents in southern Uganda
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The role of family factors in antiretroviral therapy (ART) adherence self-efficacy among HIV-infected adolescents in southern Uganda
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Journal Article
The role of family factors in antiretroviral therapy (ART) adherence self-efficacy among HIV-infected adolescents in southern Uganda
2020
Overview
Background
Adolescents living with HIV in sub-Saharan Africa are a vulnerable group at the intersection of poverty and health disparities. The family is a vital microsystem that provides financial and emotional support to achieve optimal antiretroviral therapy (ART) adherence. In this study, we explore the association between family factors and ART adherence self-efficacy, a significant psychological concept playing a critical role in ART adherence.
Methods
Data from an NIH-funded study called
Suubi + Adherence,
an economic empowerment intervention for HIV positive adolescents (average age = 12.4 years) in southern Uganda was analyzed. We conducted multilevel regression analyses to explore the protective family factors, measured by family cohesion, child-caregiver communication and perceived child-caregiver support, associated with ART adherence self-efficacy.
Results
The average age was 12.4 years and 56.4% of participants were female. The average household size was 5.7 people, with 2.3 children> 18 years. Controlling for sociodemographic and household characteristics, family cohesion (
β
= 0.397
, p
= 0.000) and child-caregiver communication (
β
= 0.118,
p
= 0.026) were significantly associated with adherence self-efficacy to ART.
Conclusion
Findings point to the need to strengthen family cohesion and communication within families if we are to enhance adherence self-efficacy among adolescents living with HIV.
Trial registration
This trial was registered with
ClinicalTrials.gov
(registration number:
NCT01790373
) on 13 February 2013.
Publisher
Springer Science and Business Media LLC,BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
Acquired immune deficiency syndrome
/ AIDS
/ Anti-Retroviral Agents - therapeutic use
/ Antiretroviral therapy adherence
/ Child
/ Children
/ Cohesion
/ Family
/ Family Relations - psychology
/ Female
/ Finance
/ Highly active antiretroviral therapy
/ HIV
/ HIV Infections - drug therapy
/ Human immunodeficiency virus
/ Humans
/ Male
/ Medication Adherence - psychology
/ Medicine
/ Poverty
/ RA1-1270
/ Studies
/ Uganda
/ Vaccine
/ Youth
