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Effectiveness of COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Frontline Workers Before and During B.1.617.2 (Delta) Variant Predominance — Eight U.S. Locations, December 2020–August 2021
by
Gaglani, Manjusha
, Groover, Kimberly
, Fowlkes, Ashley
, Tyner, Harmony
, Ellingson, Katherine
, Thiese, Matthew S.
in
Abbreviations
/ Cohort Studies
/ Confidence intervals
/ Coronaviruses
/ COVID-19
/ COVID-19 - epidemiology
/ COVID-19 - prevention & control
/ COVID-19 - virology
/ COVID-19 vaccines
/ COVID-19 Vaccines - administration & dosage
/ COVID-19 Vaccines - immunology
/ Deltas
/ Effectiveness
/ Emergency Responders - statistics & numerical data
/ Estimates
/ Full Report
/ Health Personnel - statistics & numerical data
/ Health services
/ Humans
/ Hygiene
/ Immune status
/ Immunization
/ Infection
/ Infections
/ Medical laboratories
/ Medical research
/ Medicine, Experimental
/ mRNA Vaccines
/ Pharmaceutical industry
/ Prevention
/ SARS-CoV-2 - isolation & purification
/ Severe acute respiratory syndrome coronavirus 2
/ Statistical analysis
/ Statistical models
/ Time Factors
/ United States - epidemiology
/ Vaccination - statistics & numerical data
/ Vaccine efficacy
/ Vaccines
/ Vaccines, Synthetic
/ Viral diseases
2021
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Effectiveness of COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Frontline Workers Before and During B.1.617.2 (Delta) Variant Predominance — Eight U.S. Locations, December 2020–August 2021
by
Gaglani, Manjusha
, Groover, Kimberly
, Fowlkes, Ashley
, Tyner, Harmony
, Ellingson, Katherine
, Thiese, Matthew S.
in
Abbreviations
/ Cohort Studies
/ Confidence intervals
/ Coronaviruses
/ COVID-19
/ COVID-19 - epidemiology
/ COVID-19 - prevention & control
/ COVID-19 - virology
/ COVID-19 vaccines
/ COVID-19 Vaccines - administration & dosage
/ COVID-19 Vaccines - immunology
/ Deltas
/ Effectiveness
/ Emergency Responders - statistics & numerical data
/ Estimates
/ Full Report
/ Health Personnel - statistics & numerical data
/ Health services
/ Humans
/ Hygiene
/ Immune status
/ Immunization
/ Infection
/ Infections
/ Medical laboratories
/ Medical research
/ Medicine, Experimental
/ mRNA Vaccines
/ Pharmaceutical industry
/ Prevention
/ SARS-CoV-2 - isolation & purification
/ Severe acute respiratory syndrome coronavirus 2
/ Statistical analysis
/ Statistical models
/ Time Factors
/ United States - epidemiology
/ Vaccination - statistics & numerical data
/ Vaccine efficacy
/ Vaccines
/ Vaccines, Synthetic
/ Viral diseases
2021
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Effectiveness of COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Frontline Workers Before and During B.1.617.2 (Delta) Variant Predominance — Eight U.S. Locations, December 2020–August 2021
by
Gaglani, Manjusha
, Groover, Kimberly
, Fowlkes, Ashley
, Tyner, Harmony
, Ellingson, Katherine
, Thiese, Matthew S.
in
Abbreviations
/ Cohort Studies
/ Confidence intervals
/ Coronaviruses
/ COVID-19
/ COVID-19 - epidemiology
/ COVID-19 - prevention & control
/ COVID-19 - virology
/ COVID-19 vaccines
/ COVID-19 Vaccines - administration & dosage
/ COVID-19 Vaccines - immunology
/ Deltas
/ Effectiveness
/ Emergency Responders - statistics & numerical data
/ Estimates
/ Full Report
/ Health Personnel - statistics & numerical data
/ Health services
/ Humans
/ Hygiene
/ Immune status
/ Immunization
/ Infection
/ Infections
/ Medical laboratories
/ Medical research
/ Medicine, Experimental
/ mRNA Vaccines
/ Pharmaceutical industry
/ Prevention
/ SARS-CoV-2 - isolation & purification
/ Severe acute respiratory syndrome coronavirus 2
/ Statistical analysis
/ Statistical models
/ Time Factors
/ United States - epidemiology
/ Vaccination - statistics & numerical data
/ Vaccine efficacy
/ Vaccines
/ Vaccines, Synthetic
/ Viral diseases
2021
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Effectiveness of COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Frontline Workers Before and During B.1.617.2 (Delta) Variant Predominance — Eight U.S. Locations, December 2020–August 2021
Journal Article
Effectiveness of COVID-19 Vaccines in Preventing SARS-CoV-2 Infection Among Frontline Workers Before and During B.1.617.2 (Delta) Variant Predominance — Eight U.S. Locations, December 2020–August 2021
2021
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Overview
During December 14, 2020-April 10, 2021, data from the HEROES-RECOVER Cohorts,* a network of prospective cohorts among frontline workers, showed that the Pfizer-BioNTech and Moderna mRNA COVID-19 vaccines were approximately 90% effective in preventing symptomatic and asymptomatic infection with SARS-CoV-2, the virus that causes COVID-19, in real-world conditions (1,2). This report updates vaccine effectiveness (VE) estimates including all COVID-19 vaccines available through August 14, 2021, and examines whether VE differs for adults with increasing time since completion of all recommended vaccine doses. VE before and during SARS-CoV-2 B.1.617.2 (Delta) variant predominance, which coincided with an increase in reported COVID-19 vaccine breakthrough infections, were compared (3,4).
Publisher
Centers for Disease Control & Prevention (CDC),U.S. Government Printing Office,U.S. Center for Disease Control,Centers for Disease Control and Prevention
Subject
/ COVID-19
/ COVID-19 - prevention & control
/ COVID-19 Vaccines - administration & dosage
/ COVID-19 Vaccines - immunology
/ Deltas
/ Emergency Responders - statistics & numerical data
/ Health Personnel - statistics & numerical data
/ Humans
/ Hygiene
/ SARS-CoV-2 - isolation & purification
/ Severe acute respiratory syndrome coronavirus 2
/ United States - epidemiology
/ Vaccination - statistics & numerical data
/ Vaccines
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