Journal Article

Intake of Fruit Juice and Incidence of Type 2 Diabetes: A Systematic Review and Meta-Analysis

Liu, Zhaolu, Huai, Pengcheng, Steffen, Lyn M., Xi, Bo, Tian, Huan, Zhou, Donghao, Li, Shuangshuang, Tang, Weihong, Yin, Xiuxiu

2014

Overview

Several prospective studies have been conducted to examine the relationship between fruit juice intake and risk of incident type 2 diabetes, but results have been mixed. In the present study, we aimed to estimate the association between fruit juice intake and risk of type 2 diabetes. PubMed and Embase databases were searched up to December 2013. All prospective cohort studies of fruit juice intake with risk of type 2 diabetes were included. The pooled relative risks (RRs) with 95% confidence intervals (CIs) for highest vs. lowest category of fruit juice intake were estimated using a random-effects model. A total of four studies (191,686 participants, including 12,375 with type 2 diabetes) investigated the association between sugar-sweetened fruit juice and risk of incident type 2 diabetes, and four studies (137,663 participants and 4,906 cases) investigated the association between 100% fruit juice and risk of incident type 2 diabetes. A higher intake of sugar-sweetened fruit juice was significantly associated with risk of type 2 diabetes (RR = 1.28, 95%CI = 1.04-1.59, p = 0.02), while intake of 100% fruit juice was not associated with risk of developing type 2 diabetes (RR = 1.03, 95% CI = 0.91-1.18, p = 0.62). Our findings support dietary recommendations to limit sugar-sweetened beverages, such as fruit juice with added sugar, to prevent the development of type 2 diabetes.

• Publisher: Public Library of Science,Public Library of Science (PLoS)
• Subject: Adult / Analysis / Beverages / Beverages - adverse effects / Bias / Biology and Life Sciences / Childrens health / Confidence intervals / Development and progression / Diabetes / Diabetes mellitus / Diabetes Mellitus, Type 2 - etiology / Diet / Diet - adverse effects / Dietary Sucrose - adverse effects / Epidemiology / Exercise / Fruit - adverse effects / Fruit juices / Fruits / Health risk assessment / Health risks / Humans / Incidence / Juices (Beverages) / Maternal & child health / Medicine and Health Sciences / Meta-analysis / Middle Aged / Obesity / Physical Sciences / Prospective Studies / Public health / Research and Analysis Methods / Risk / Risk assessment / Risk Factors / Statistical analysis / Studies / Sugar / Sweetening Agents - adverse effects / Systematic review / Type 2 diabetes