Journal Article

Acute changes in handgrip strength, lung function and health-related quality of life following cardiac surgery

Jones, Anne, Saxena, Pankaj, Leicht, Anthony, Mgbemena, Nnamdi, Senthuran, Siva, Ang, Nicholas

2022

Overview

Handgrip strength (HGS), lung function and health-related quality of life (HRQoL) are relevant indicators of future cardiovascular risk and mortality. The impact of cardiac surgery on these predictive variables has been under-explored. The aim of this study was to determine the acute (within hospital) changes in HGS, lung function and HRQoL, and their relationships, in adults undergoing elective cardiac surgery. Further, the study examined the relationship between these variables and the predictors for lung function and HRQoL in these patients. The study was a prospective cohort study that involved 101 patients who completed pre-operative (1-2 days before surgery) and physiotherapy discharge (5-7 days after surgery) assessments. Handgrip strength, lung function and HRQoL were assessed using JAMAR dynamometers, Vitalograph-Alpha or EasyOne spirometer, and Short-Form 36 questionnaire, respectively. Changes in these variables and their relationships were analysed using paired t-test and Pearson correlation coefficients, respectively. Prediction of lung function and HRQoL using HGS and other co-variates was conducted using regression analysis. At the time of physiotherapy discharge, lung function, HGS and the physical component of HRQoL were significantly (<0.001) reduced compared to their pre-operative values. Significant (<0.001) and moderate correlations were identified between HGS and lung function at pre-operation and physiotherapy discharge. Handgrip strength was a significant predictor of lung function pre-operatively but not at physiotherapy discharge. Pre-operative lung function and HRQoL, as well as other variables, were significant predictors of lung function and HRQoL during physiotherapy discharge. Undergoing cardiac surgery acutely and significantly reduced lung function, HGS and physical component of HRQoL in adults with cardiac disease. Assessment of HGS at physiotherapy discharge may be a poor indicator of operative changes in lung function and HRQoL. Clinicians may consider HGS as an inadequate tool in predicting lung function and HRQoL following cardiac surgery.

• Publisher: Public Library of Science,Public Library of Science (PLoS)
• Subject: Adults / Aged / Biology and Life Sciences / Cardiac Surgical Procedures - adverse effects / Cardiovascular diseases / Coronary artery disease / Correlation / Correlation coefficient / Correlation coefficients / Disease / Dynamometers / Elective Surgical Procedures - adverse effects / Evaluation / Female / Grip strength / Hand Strength / Health aspects / Health risks / Heart / Heart diseases / Heart Diseases - surgery / Heart surgery / Hospitals / Humans / Hydraulics / Intensive care / Length of stay / Lung - physiopathology / Lungs / Male / Mathematical analysis / Medical records / Medicine / Medicine and Health Sciences / Middle Aged / Pain / Patient Discharge / Patients / Physical therapy / Postoperative Complications - etiology / Prospective Studies / Quality of Life / Recovery (Medical) / Regression analysis / Respiratory function / Respiratory Function Tests / Self Report / Surgery / Treatment Outcome / Variables