Journal Article

Psychosocial job exposure and risk of coronary artery calcification

Mia Söderberg, Eva Andersson, Annika Rosengren, Kjell Torén, Helena Eriksson

2021

Overview

The aim was to examine potential associations between psychosocial job exposures, evaluated with the Job Demand-Control-model, and presence of coronary artery calcium. We performed a cross-sectional study using the Swedish CArdioPulmonary bioImage Study,(SCAPIS)pilot study. Coronary artery calcium was assessed through computed tomography of the coronary arteries and with coronary artery scoring, CACS. Main outcome was CACS [greater than or equal to]100 compared to CACS 0. Job demand and control was analysed according to the standard categorization of the two variables into: high strain, active, passive and low strain (reference). Associations between these variables and CACS were calculated with prevalence ratios (PR) using Cox regression with robust variance, 95% confidence intervals (CI) and adjusted for age, smoking, education, socioeconomic area and metabolic syndrome. In total 777 participants were used in our analyses, for which 20% of the men and 5% of the women had CACS [greater than or equal to]100, respectively. The PR of having CACS [greater than or equal to]100 was non-significantly elevated for men in high strain jobs 1.54 (95% CI 0.88-2.69) and in active jobs 1.67 (95% CI 0.92-3.06), adjusted for covariates. For women there was no association between exposure to high strain and having CACS [greater than or equal to]100 PR 1.02 (95% CI 0.24-4.31). Among women reporting passive job, the PR was non-significantly elevated, 2.40 (95% CI 0.83-6.92), adjusted for covariates. The statistical power of the study was limited, but our results suggests the possibility that exposure to a high strain or an active job situation may increase the risk of CACS in men, while in women, it may rather be exposure to passive job.

• Publisher: Public Library of Science (PLoS),Public Library of Science
• Subject: Arbetsmedicin och miljömedicin / atherosclerosis / Biology and Life Sciences / blood / Blood pressure / Calcification / Calcification (ectopic) / calcium / Cardiovascular disease / Cardiovascular diseases / Cholesterol / Confidence Intervals / Coronary artery / Coronary artery disease / Coronary heart disease / Coronary vessels / Cross-Sectional Studies / demand-control-support / Diabetes mellitus / Editing / Environmental health / Eriksson, Eva / Female / Health aspects / Health risks / Health services / Heart diseases / heart-disease / High density lipoprotein / Hospitals / Humans / Hypertension / Insulin / Job stress / Male / Medicine / Medicine and Health Sciences / Metabolic disorders / Metabolic Syndrome / Occupational exposure / Occupational health / Occupational Health and Environmental Health / Occupational stress / predict / Proportional Hazards Models / Public health / Q / quantification / Questionnaires / R / Risk factors / Science / Science & Technology - Other Topics / Social Sciences / Socioeconomic Factors / Statins / strain / Triglycerides / Variables / Veins & arteries / Womens health / Working conditions