Asset Details
Do you wish to reserve the book?
The interdependent hemodynamic influence between abdominal aortic aneurysm and renal artery stenosis
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
The interdependent hemodynamic influence between abdominal aortic aneurysm and renal artery stenosis
Do you wish to request the book?
The interdependent hemodynamic influence between abdominal aortic aneurysm and renal artery stenosis
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
The interdependent hemodynamic influence between abdominal aortic aneurysm and renal artery stenosis
2024
Overview
Cardiovascular diseases remain a leading cause of morbidity and mortality worldwide with abdominal aortic aneurysm (AAA) and renal artery stenosis (RAS) standing out as significant contributors to the vascular pathology spectrum. While these conditions have traditionally been approached as distinct entities, emerging evidence suggests a compelling interdependent relationship between AAA and RAS, challenging the conventional siloed understanding. The confluence of AAA and RAS represents a complex interplay within the cardiovascular system, one that is often overlooked in clinical practice and research. Here, we reveal a bidirectional consequential impact between these two diseases. The location of the AAA sac was investigated for its specific influence on the risk of RAS development. Although studies have shown a higher coincidence between the suprarenal AAA and RAS, our findings demonstrated that the presence of a suprarenal AAA correlated with the lowest risk of RAS development among the three investigated AAA locations. Notably, we also highlighted that the pre-existence of stenosis in the renal artery poses an elevated risk for the formation of suprarenal AAA, assessed by an increased wall shear stress gradient on the aortic wall. Our findings prompt a paradigm shift in the understanding and treatment of AAA and RAS in clinical practice.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
