Journal Article

Autoreject: Automated artifact rejection for MEG and EEG data

Bekhti, Yousra, Jas, Mainak, Gramfort, Alexandre, Engemann, Denis A., Raimondo, Federico

2017

Overview

We present an automated algorithm for unified rejection and repair of bad trials in magnetoencephalography (MEG) and electroencephalography (EEG) signals. Our method capitalizes on cross-validation in conjunction with a robust evaluation metric to estimate the optimal peak-to-peak threshold – a quantity commonly used for identifying bad trials in M/EEG. This approach is then extended to a more sophisticated algorithm which estimates this threshold for each sensor yielding trial-wise bad sensors. Depending on the number of bad sensors, the trial is then repaired by interpolation or by excluding it from subsequent analysis. All steps of the algorithm are fully automated thus lending itself to the name Autoreject. In order to assess the practical significance of the algorithm, we conducted extensive validation and comparisons with state-of-the-art methods on four public datasets containing MEG and EEG recordings from more than 200 subjects. The comparisons include purely qualitative efforts as well as quantitatively benchmarking against human supervised and semi-automated preprocessing pipelines. The algorithm allowed us to automate the preprocessing of MEG data from the Human Connectome Project (HCP) going up to the computation of the evoked responses. The automated nature of our method minimizes the burden of human inspection, hence supporting scalability and reliability demanded by data analysis in modern neuroscience. [Display omitted] •A strategy for artifact rejection in M/EEG using peak-to-peak thresholds is proposed•The thresholds are estimated using cross-validation with a robust error metric•The method detects and repairs outlier data segments for each sensor•Comparison with competing methods on 200 subjects with ground truth responses

• Publisher: Elsevier Inc,Elsevier Limited,Elsevier
• Subject: Algorithms / Artificial intelligence / Automated analysis / Automation / Brain - physiology / Brain Mapping - methods / Computer Science / Cross-validation / Data processing / EEG / electroencephalogram / Electroencephalogram (EEG) / Electroencephalography / Electroencephalography - methods / Engineering, computing & technology / Human Connectome Project (HCP) / Humans / Ingénierie, informatique & technologie / Life Sciences / Machine Learning / Magnetoencephalography / Magnetoencephalography (MEG) / Magnetoencephalography - methods / Medical Imaging / meg / Methods / Models, Neurological / Nervous system / Preprocessing / Sensors / Signal Processing, Computer-Assisted / Statistical learning / Statistics