Asset Details
Do you wish to reserve the book?
Hxt1, a monosaccharide transporter and sensor required for virulence of the maize pathogen Ustilago maydis
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Hxt1, a monosaccharide transporter and sensor required for virulence of the maize pathogen Ustilago maydis
Do you wish to request the book?
Hxt1, a monosaccharide transporter and sensor required for virulence of the maize pathogen Ustilago maydis
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Hxt1, a monosaccharide transporter and sensor required for virulence of the maize pathogen Ustilago maydis
2015
Overview
The smut Ustilago maydis, a ubiquitous pest of corn, is highly adapted to its host to parasitize on its organic carbon sources. We have identified a hexose transporter, Hxt1, as important for fungal development during both the saprophytic and the pathogenic stage of the fungus.
Hxt1 was characterized as a high-affinity transporter for glucose, fructose, and mannose; ∆hxt1 strains show significantly reduced growth on these substrates, setting Hxt1 as the main hexose transporter during saprophytic growth.
After plant infection, ∆hxt1 strains show decreased symptom development. However, expression of a Hxt1 protein with a mutation leading to constitutively active signaling in the yeast glucose sensors Snf3p and Rgt2p results in completely apathogenic strains. Fungal development is stalled immediately after plant penetration, implying a dual function of Hxt1 as transporter and sensor.
As glucose sensors are only known for yeasts, ‘transceptor’ as Hxt1 may constitute a general mechanism for sensing of glucose in fungi. In U. maydis, Hxt1 links a nutrient-dependent environmental signal to the developmental program during pathogenic development.
Publisher
New Phytologist Trust,Wiley Subscription Services, Inc
Subject
/ carbon
/ corn
/ fructose
/ Fungal Proteins - metabolism
/ Fungal Proteins - physiology
/ Fungi
/ Glucose
/ Hexose
/ Mannans
/ Mannose
/ Monosaccharide Transport Proteins - genetics
/ Monosaccharide Transport Proteins - metabolism
/ Monosaccharide Transport Proteins - physiology
/ Mutation
/ pests
/ Sensors
/ Smut
/ Virulence Factors - genetics
/ Virulence Factors - metabolism
/ Virulence Factors - physiology
/ Yeast
/ Yeasts
/ Zea mays
