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Trends and demographic patterns in biologic and corticosteroid prescriptions for inflammatory bowel disease: findings from electronic medical records, 2011–2020
by
Carlson, Susan
, Greenlund, Kurt
, Xu, Fang
, Liu, Yong
in
Adrenal Cortex Hormones - therapeutic use
/ Age groups
/ Alcohol use
/ anti-inflammatory agents
/ anti-inflammatory agents, non-steroidal
/ Archives & records
/ Biological products
/ Biological Products - therapeutic use
/ Brief report
/ Chronic Disease
/ Clinical outcomes
/ Codes
/ Colitis, Ulcerative - drug therapy
/ Colitis, Ulcerative - epidemiology
/ Computerized medical records
/ Crohn Disease - drug therapy
/ Crohn Disease - epidemiology
/ Crohn's disease
/ Cross-Sectional Studies
/ Demographics
/ Demography
/ Disease
/ Drug Prescriptions
/ Electronic Health Records
/ Ethnicity
/ Female
/ Hispanic people
/ Humans
/ Inflammatory bowel disease
/ inflammatory bowel diseases
/ Inflammatory Bowel Diseases - drug therapy
/ Inflammatory Bowel Diseases - epidemiology
/ Information technology
/ Lifestyles
/ Male
/ Medical records
/ Medical treatment
/ Patients
/ Prescription drugs
/ Prescriptions
/ Regression analysis
/ Remission (Medicine)
/ Risk factors
/ Smoking
/ Steroids
/ Therapy progress assessment
/ Trends
/ Ulcerative colitis
/ Women
2022
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Trends and demographic patterns in biologic and corticosteroid prescriptions for inflammatory bowel disease: findings from electronic medical records, 2011–2020
by
Carlson, Susan
, Greenlund, Kurt
, Xu, Fang
, Liu, Yong
in
Adrenal Cortex Hormones - therapeutic use
/ Age groups
/ Alcohol use
/ anti-inflammatory agents
/ anti-inflammatory agents, non-steroidal
/ Archives & records
/ Biological products
/ Biological Products - therapeutic use
/ Brief report
/ Chronic Disease
/ Clinical outcomes
/ Codes
/ Colitis, Ulcerative - drug therapy
/ Colitis, Ulcerative - epidemiology
/ Computerized medical records
/ Crohn Disease - drug therapy
/ Crohn Disease - epidemiology
/ Crohn's disease
/ Cross-Sectional Studies
/ Demographics
/ Demography
/ Disease
/ Drug Prescriptions
/ Electronic Health Records
/ Ethnicity
/ Female
/ Hispanic people
/ Humans
/ Inflammatory bowel disease
/ inflammatory bowel diseases
/ Inflammatory Bowel Diseases - drug therapy
/ Inflammatory Bowel Diseases - epidemiology
/ Information technology
/ Lifestyles
/ Male
/ Medical records
/ Medical treatment
/ Patients
/ Prescription drugs
/ Prescriptions
/ Regression analysis
/ Remission (Medicine)
/ Risk factors
/ Smoking
/ Steroids
/ Therapy progress assessment
/ Trends
/ Ulcerative colitis
/ Women
2022
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Trends and demographic patterns in biologic and corticosteroid prescriptions for inflammatory bowel disease: findings from electronic medical records, 2011–2020
by
Carlson, Susan
, Greenlund, Kurt
, Xu, Fang
, Liu, Yong
in
Adrenal Cortex Hormones - therapeutic use
/ Age groups
/ Alcohol use
/ anti-inflammatory agents
/ anti-inflammatory agents, non-steroidal
/ Archives & records
/ Biological products
/ Biological Products - therapeutic use
/ Brief report
/ Chronic Disease
/ Clinical outcomes
/ Codes
/ Colitis, Ulcerative - drug therapy
/ Colitis, Ulcerative - epidemiology
/ Computerized medical records
/ Crohn Disease - drug therapy
/ Crohn Disease - epidemiology
/ Crohn's disease
/ Cross-Sectional Studies
/ Demographics
/ Demography
/ Disease
/ Drug Prescriptions
/ Electronic Health Records
/ Ethnicity
/ Female
/ Hispanic people
/ Humans
/ Inflammatory bowel disease
/ inflammatory bowel diseases
/ Inflammatory Bowel Diseases - drug therapy
/ Inflammatory Bowel Diseases - epidemiology
/ Information technology
/ Lifestyles
/ Male
/ Medical records
/ Medical treatment
/ Patients
/ Prescription drugs
/ Prescriptions
/ Regression analysis
/ Remission (Medicine)
/ Risk factors
/ Smoking
/ Steroids
/ Therapy progress assessment
/ Trends
/ Ulcerative colitis
/ Women
2022
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Trends and demographic patterns in biologic and corticosteroid prescriptions for inflammatory bowel disease: findings from electronic medical records, 2011–2020
Journal Article
Trends and demographic patterns in biologic and corticosteroid prescriptions for inflammatory bowel disease: findings from electronic medical records, 2011–2020
2022
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Overview
Prescriptions for biologic therapy for treatment of Crohn’s disease (CD) and ulcerative colitis (UC) have increased during the past two decades; however, trends are less clear regarding corticosteroid prescriptions in this context. We designed a cross-sectional study using the IQVIA Ambulatory Electronic Medical Records databases. Weighted linear regressions by age group were used to estimate annual percentage change from 2011 to 2020 in prescriptions for biologics and for corticosteroids among patients with or without biologic prescriptions within the same calendar year. Using 2019 data, we compared patient demographic and lifestyle risk factors using χ2 test for biologic prescriptions and corticosteroids with or without biologics prescriptions. There was an 11% (CD) and 16% (UC) annual increase in the percentage of patients prescribed biologics during the study period. The percentage of patients with biologics prescriptions prescribed corticosteroids decreased by 2% (CD) and 3% (UC) annually after 2015, while the percentage remained unchanged for corticosteroid prescriptions among patients without biologics. In 2019, differences in medication prescriptions existed by patient’s demographic and lifestyle factors for patients with CD (n=52,892) and UC (n=52,280), including a higher percentage prescribed biologics among younger patients, men, those with fewer comorbidities, and current alcohol drinkers, and a higher percentage prescribed corticosteroids without biologics among women, those with more comorbidities, and a history of smoking. While medications continue to evolve during the biologic era, it is important to continue to monitor trends and differences in prescription patterns to assess progress toward optimizing treatment for patients with CD or UC.
Publisher
BMJ Publishing Group Ltd,SAGE Publications,Sage Publications Ltd
Subject
Adrenal Cortex Hormones - therapeutic use
/ anti-inflammatory agents, non-steroidal
/ Biological Products - therapeutic use
/ Codes
/ Colitis, Ulcerative - drug therapy
/ Colitis, Ulcerative - epidemiology
/ Computerized medical records
/ Crohn Disease - drug therapy
/ Crohn Disease - epidemiology
/ Disease
/ Female
/ Humans
/ Inflammatory Bowel Diseases - drug therapy
/ Inflammatory Bowel Diseases - epidemiology
/ Male
/ Patients
/ Smoking
/ Steroids
/ Trends
/ Women
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