Asset Details
Do you wish to reserve the book?
Nano-curcumin potentially ameliorates hormonal function and follicular counts following the vitrification and transplantation of rat ovarian tissue
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Nano-curcumin potentially ameliorates hormonal function and follicular counts following the vitrification and transplantation of rat ovarian tissue
Do you wish to request the book?
Nano-curcumin potentially ameliorates hormonal function and follicular counts following the vitrification and transplantation of rat ovarian tissue
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Nano-curcumin potentially ameliorates hormonal function and follicular counts following the vitrification and transplantation of rat ovarian tissue
2025
Overview
Ovarian tissue cryopreservation followed by transplantation may damage the ovaries, potentially impeding fertility restoration. The notable antioxidant properties of curcumin highlight its potential as a therapeutic agent for enhancing fertility restoration. The use of nano-curcumin to improve ovarian tissue transplantation outcomes after vitrification for fertility preservation remains unknown. This study aimed to evaluate endocrine function, by measuring estradiol (E2), follicle-stimulating hormone (FSH), and anti-Müllerian hormone (AMH), and ovarian follicle count in rats subjected to vitrification and transplantation. Thirty female rats were categorized into three groups (
n
= 10/group): control (Group 1), untreated (Group 2), and nano-curcumin treated (Group 3; 2 mg/kg/day for 14 days). The rats were euthanized, and blood samples and ovaries were collected for analysis. The FSH level in the treated group (0.99 (0.97-1.00) mIU/ml) was significantly lower compared to that in the other groups, with a significant difference, particularly against Group 2 (
p
< 0.05). E2 and AMH values were higher in the treated group, with increased primordial and total follicle counts, though not statistically significant (
p
= 0.069 and
p
= 0.051). The administration of nano-curcumin may improve hormonal function and increase the number of follicles in rat ovaries after vitrification and transplantation.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
/ 631/443
/ 639/301
/ 639/925
/ 692/163
/ 692/308
/ Animals
/ Anti-Mullerian Hormone - blood
/ Anti-Mullerian Hormone - metabolism
/ Curcumin
/ Curcumin - administration & dosage
/ Female
/ Fertility Preservation - methods
/ Follicle Stimulating Hormone - blood
/ Follicle Stimulating Hormone - metabolism
/ Follicle-stimulating hormone
/ Humanities and Social Sciences
/ Ischemia
/ Ovarian Follicle - drug effects
/ Ovarian Follicle - transplantation
/ Ovaries
/ Rats
/ Science
/ Trends
