Asset Details
Do you wish to reserve the book?
Effectiveness of post-exposure prophylaxis during varicella outbreaks among primary and middle school students in Shanghai: An analysis of three-year surveillance data
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Effectiveness of post-exposure prophylaxis during varicella outbreaks among primary and middle school students in Shanghai: An analysis of three-year surveillance data
Do you wish to request the book?
Effectiveness of post-exposure prophylaxis during varicella outbreaks among primary and middle school students in Shanghai: An analysis of three-year surveillance data
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Effectiveness of post-exposure prophylaxis during varicella outbreaks among primary and middle school students in Shanghai: An analysis of three-year surveillance data
2018
Overview
•First 3-year large data emergency vaccination post-exposure prophylaxis study.•Varicella outbreaks in one-dose regime areas more likely in schools.•Emergency vaccinations effective within 3 days of exposure in prior vaccinated.•Emergency vaccinations control school outbreaks in one-dose varicella regime areas.
To evaluate the effectiveness of post-exposure prophylaxis conducted during varicella outbreaks among students in Shanghai.
Surveillance data were collected from September 1, 2013 to December 31, 2016 involving 3524 susceptible students in 109 primary and middle school classes where emergency vaccinations (EVs) had been administered. Students were divided into two groups according to their prior vaccination (PV) varicella vaccine status. A secondary attack rate was used to compare EV and non-EV groups using a chi-squared test. Stratification analyses were performed, adjusting for the EV administration date, the vaccination coverage rate, and the number of cases prior to the EV.
The effectiveness rate was 92.2% (95% confidence interval (CI): 37.1–99.0%) when EV was applied within 3 days following the outbreak onset date, and 95.2% (95% CI: 79.9–98.8%) when vaccination coverage was ≥80% among students with PV. When students with PV received an EV for varicella within 3 days, the effectiveness rate was 100%.
EV showed high protective effectiveness for varicella during outbreaks, especially if administered within 3 days of an outbreak and in conjunction with a high coverage rate.
Publisher
Elsevier Ltd,Elsevier Limited
Subject
/ Chickenpox - prevention & control
/ Chickenpox Vaccine - administration & dosage
/ Child
/ China
/ Disease Outbreaks - statistics & numerical data
/ Female
/ Herpesvirus 3, Human - immunology
/ Humans
/ Male
/ Post-Exposure Prophylaxis - statistics & numerical data
/ Schools
/ Students
/ Vaccination - statistics & numerical data
/ Vaccines
