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Very high prevalence of 25-hydroxyvitamin D deficiency in 6433 UK South Asian adults: analysis of the UK Biobank Cohort
by
Lanham-New, Susan A.
, Blackbourn, David J.
, Ahmadi, Kourosh R.
, Darling, Andrea L.
in
25-Hydroxyvitamin D
/ Adult
/ Aged
/ Asian People
/ Biobanks
/ Biological Specimen Banks
/ blood serum
/ Calciferol
/ Cohort analysis
/ Cohort Studies
/ cross-sectional studies
/ Databases, Factual
/ Demography
/ Diet
/ Dietary supplements
/ Dietary Surveys and Nutritional Epidemiology
/ England
/ Epidemiology
/ fatty fish
/ Female
/ Fish oils
/ Health promotion
/ Humans
/ Interactive computer systems
/ Male
/ males
/ Middle Aged
/ Nutrition research
/ Prevalence
/ Public health
/ Questionnaires
/ Regression analysis
/ sample size
/ Scotland
/ Seasons
/ Software
/ spring
/ summer
/ United Kingdom
/ Variables
/ vegetarian diet
/ Vegetarianism
/ Vitamin D
/ Vitamin D - analogs & derivatives
/ Vitamin D - blood
/ Vitamin D Deficiency - epidemiology
/ Vitamin D Deficiency - ethnology
/ Vitamin deficiency
/ Winter
/ Women
2021
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Very high prevalence of 25-hydroxyvitamin D deficiency in 6433 UK South Asian adults: analysis of the UK Biobank Cohort
by
Lanham-New, Susan A.
, Blackbourn, David J.
, Ahmadi, Kourosh R.
, Darling, Andrea L.
in
25-Hydroxyvitamin D
/ Adult
/ Aged
/ Asian People
/ Biobanks
/ Biological Specimen Banks
/ blood serum
/ Calciferol
/ Cohort analysis
/ Cohort Studies
/ cross-sectional studies
/ Databases, Factual
/ Demography
/ Diet
/ Dietary supplements
/ Dietary Surveys and Nutritional Epidemiology
/ England
/ Epidemiology
/ fatty fish
/ Female
/ Fish oils
/ Health promotion
/ Humans
/ Interactive computer systems
/ Male
/ males
/ Middle Aged
/ Nutrition research
/ Prevalence
/ Public health
/ Questionnaires
/ Regression analysis
/ sample size
/ Scotland
/ Seasons
/ Software
/ spring
/ summer
/ United Kingdom
/ Variables
/ vegetarian diet
/ Vegetarianism
/ Vitamin D
/ Vitamin D - analogs & derivatives
/ Vitamin D - blood
/ Vitamin D Deficiency - epidemiology
/ Vitamin D Deficiency - ethnology
/ Vitamin deficiency
/ Winter
/ Women
2021
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Very high prevalence of 25-hydroxyvitamin D deficiency in 6433 UK South Asian adults: analysis of the UK Biobank Cohort
by
Lanham-New, Susan A.
, Blackbourn, David J.
, Ahmadi, Kourosh R.
, Darling, Andrea L.
in
25-Hydroxyvitamin D
/ Adult
/ Aged
/ Asian People
/ Biobanks
/ Biological Specimen Banks
/ blood serum
/ Calciferol
/ Cohort analysis
/ Cohort Studies
/ cross-sectional studies
/ Databases, Factual
/ Demography
/ Diet
/ Dietary supplements
/ Dietary Surveys and Nutritional Epidemiology
/ England
/ Epidemiology
/ fatty fish
/ Female
/ Fish oils
/ Health promotion
/ Humans
/ Interactive computer systems
/ Male
/ males
/ Middle Aged
/ Nutrition research
/ Prevalence
/ Public health
/ Questionnaires
/ Regression analysis
/ sample size
/ Scotland
/ Seasons
/ Software
/ spring
/ summer
/ United Kingdom
/ Variables
/ vegetarian diet
/ Vegetarianism
/ Vitamin D
/ Vitamin D - analogs & derivatives
/ Vitamin D - blood
/ Vitamin D Deficiency - epidemiology
/ Vitamin D Deficiency - ethnology
/ Vitamin deficiency
/ Winter
/ Women
2021
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Very high prevalence of 25-hydroxyvitamin D deficiency in 6433 UK South Asian adults: analysis of the UK Biobank Cohort
Journal Article
Very high prevalence of 25-hydroxyvitamin D deficiency in 6433 UK South Asian adults: analysis of the UK Biobank Cohort
2021
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Overview
Little research has assessed serum 25-hydroxyvitamin D (25(OH)D) concentration and its predictors in Western-dwelling South Asians in a relatively large sample size. This observational, cross-sectional analysis assessed baseline prevalence of 25(OH)D deficiency in UK-dwelling South Asians (aged 40–69 years, 2006–2010) from the UK Biobank Cohort. Serum 25(OH)D measurements were undertaken using the DiaSorin Liaison XL assay. Of 6433 South Asians with a 25(OH)D measurement, using commonly used cut-off thresholds, 55 % (n 3538) had 25(OH)D < 25 nmol/l (severe deficiency) and 92 % (n 5918) had 25(OH)D < 50 nmol/l (insufficiency). Of the participants with a measurement, 20 % (n 1287) had 25(OH)D concentration <15 nmol/l (very severe deficiency). When 824 participants with undetectable (<10 nmol/l) 25(OH)D measurements were included (total n 7257), 29 % (n 2105) had 25(OH)D < 15 nmol/l, 60 % (n 4354) had 25(OH)D < 25 nmol/l and 93 % (n 6749) had 25(OH)D < 50 nmol/l. Logistic regression predictors of 25(OH)D < 25 nmol/l included the following characteristics: being male; Pakistani; higher BMI; 40–59 years old; never consuming oily fish; summer sun exposure <5 h/d, not using a vitamin D-containing supplement, measurement in winter or spring and vegetarianism. In terms of region, median 25(OH)D concentration was 19–20 nmol/l in Scotland, Northern England, the Midlands and Wales. Across Southern England and London, it was slightly higher at 24–25 nmol/l. Our analyses suggest the need for increased awareness of vitamin D deficiency in South Asians as well as urgent public health interventions to prevent and treat vitamin D deficiency in this group.
Publisher
Cambridge University Press
Subject
/ Adult
/ Aged
/ Biobanks
/ Diet
/ Dietary Surveys and Nutritional Epidemiology
/ England
/ Female
/ Humans
/ Interactive computer systems
/ Male
/ males
/ Scotland
/ Seasons
/ Software
/ spring
/ summer
/ Vitamin D - analogs & derivatives
/ Vitamin D Deficiency - epidemiology
/ Vitamin D Deficiency - ethnology
/ Winter
/ Women
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