Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Triple Therapy for Cystic Fibrosis Phe508del–Gating and –Residual Function Genotypes

by Moskowitz, Samuel M , Polineni, Deepika , Fajac, Isabelle , Ramsey, Bonnie W , Tullis, Elizabeth , Ahluwalia, Neil , Tian, Simon , Barry, Peter J , Álvarez, Antonio , de Winter-de Groot, Karin M , Mall, Marcus A , Taylor-Cousar, Jennifer L , Zhang, Yaohua , Waltz, David , Xuan, Fengjuan , Rowe, Steven M , Colombo, Carla , Jun, Lucy S , Sutharsan, Sivagurunathan , McBennett, Kimberly A , McKone, Edward F , Prieto-Centurion, Valentin

in Adolescent / Adolescent Medicine / Adult / Adverse events / Alleles / Aminophenols / Aminophenols - adverse effects / Aminophenols - therapeutic use / Benzodioxoles / Benzodioxoles - adverse effects / Benzodioxoles - therapeutic use / Child / Chloride / Chloride Channel Agonists / Chloride Channel Agonists - adverse effects / Chloride Channel Agonists - therapeutic use / Chlorides / Chlorides - analysis / Collaboration / COVID-19 / Critical Care / Critical Care General / Cystic Fibrosis / Cystic Fibrosis - drug therapy / Cystic Fibrosis - genetics / Cystic Fibrosis Transmembrane Conductance Regulator / Cystic Fibrosis Transmembrane Conductance Regulator - genetics / Design / Double-Blind Method / Drug Combinations / Female / Gating / Genetics / Genetics General / Genotype / Genotypes / Human health and pathology / Humans / Indoles / Indoles - adverse effects / Indoles - therapeutic use / Life Sciences / Male / Mutation / Patients / Pediatrics / Pharmaceuticals / Proteins / Pulmonary / Pyrazoles / Pyrazoles - adverse effects / Pyrazoles - therapeutic use / Pyridines / Pyridines - adverse effects / Pyridines - therapeutic use / Quality of life / Quinolines / Quinolines - adverse effects / Quinolines - therapeutic use / Statistical analysis / Sweat / Sweat - chemistry / Teenagers

2021

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

Triple Therapy for Cystic Fibrosis Phe508del–Gating and –Residual Function Genotypes

2021

Confirm

Do you wish to request the book?

Triple Therapy for Cystic Fibrosis Phe508del–Gating and –Residual Function Genotypes

2021

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Triple Therapy for Cystic Fibrosis Phe508del–Gating and –Residual Function Genotypes

Moskowitz, Samuel M,

Polineni, Deepika,

Fajac, Isabelle,

Ramsey, Bonnie W,

Tullis, Elizabeth,

Ahluwalia, Neil,

Tian, Simon,

Barry, Peter J,

Álvarez, Antonio,

de Winter-de Groot, Karin M,

Mall, Marcus A,

Taylor-Cousar, Jennifer L,

Zhang, Yaohua,

Waltz, David,

Xuan, Fengjuan,

Rowe, Steven M,

Colombo, Carla,

Jun, Lucy S,

Sutharsan, Sivagurunathan,

McBennett, Kimberly A,

McKone, Edward F,

Prieto-Centurion, Valentin

2021

Overview

Elexacaftor–ivacaftor–tezacaftor therapy is efficacious in cystic fibrosis among patients with at least one copy of the Phe508del allele. In this trial involving patients with either a gating or residual function allele in addition to the Phe508del allele, elexacaftor–ivacaftor–tezacaftor improved lung function as compared with active control therapy.

Share this book

Add to My Shelf

Publisher

Massachusetts Medical Society

Subject

Adolescent

/ Adolescent Medicine

/ Adult

/ Adverse events

/ Alleles

/ Aminophenols

/ Aminophenols - adverse effects