Journal Article

Nanostructured Metal Oxide-Based Electrochemical Biosensors in Medical Diagnosis

Keles, Gulsu, Sifa Ataman, Elif, Kurbanoglu, Sevinc, Taskin, Sueda Betul, Polatoglu, İlker

2024

Overview

Nanostructured metal oxides (NMOs) provide electrical properties such as high surface-to-volume ratio, reaction activity, and good adsorption strength. Furthermore, they serve as a conductive substrate for the immobilization of biomolecules, exhibiting notable biological activity. Capitalizing on these characteristics, they find utility in the development of various electrochemical biosensing devices, elevating the sensitivity and selectivity of such diagnostic platforms. In this review, different types of NMOs, including zinc oxide (ZnO), titanium dioxide (TiO2), iron (II, III) oxide (Fe3O4), nickel oxide (NiO), and copper oxide (CuO); their synthesis methods; and how they can be integrated into biosensors used for medical diagnosis are examined. It also includes a detailed table for the last 10 years covering the morphologies, analysis techniques, analytes, and analytical performances of electrochemical biosensors developed for medical diagnosis.

• Publisher: MDPI AG
• Subject: Biological activity / Biomolecules / Biosensing Techniques / biosensor / Biosensors / Chemical properties / Chemical synthesis / Copper - analysis / Copper - chemistry / Copper oxides / Cost analysis / Diagnosis / Diagnostic equipment (Medical) / Electric properties / Electrical properties / Electrochemical Techniques / Electrochemistry / Enzymes / Equipment and supplies / Humans / Immobilization / Iron oxides / Materials / medical diagnosis / metal oxide nanomaterials / Metal oxide semiconductors / Metal oxides / Metallic oxides / Metals - chemistry / Nanomaterials / Nanoparticles / Nanostructure / Nanostructures / Nanowires / Nickel / Nickel - chemistry / Nickel oxides / Oxides - chemistry / Quantum dots / Sensors / Substrates / Titanium / Titanium - chemistry / Titanium dioxide / Zinc oxide / Zinc Oxide - chemistry