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Trends in parkinson’s disease mortality in China from 2004 to 2021: a joinpoint analysis
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Trends in parkinson’s disease mortality in China from 2004 to 2021: a joinpoint analysis
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Journal Article
Trends in parkinson’s disease mortality in China from 2004 to 2021: a joinpoint analysis
2024
Overview
Background
This study aimed to analyze the trends of Parkinson’s disease (PD) mortality rates among Chinese residents from 2004 to 2021, provide evidence for the formulation of PD prevention and control strategies to improve the quality of life among PD residents.
Methods
Demographic and sociological data such as gender, urban or rural residency and age were obtained from the National Cause of Death Surveillance Dataset from 2004 to 2021. We then analyzed the trends of PD mortality rates by Joinpoint regression.
Results
The PD mortality and standardized mortality rates in China showed an overall increasing trend during 2004–2021 (average annual percentage change [AAPC] = 7.14%, AAPC
ASMR
=3.21%,
P
< 0.001). The mortality and standardized mortality rate in male (AAPC = 7.65%, AAPC
ASMR
=3.18%,
P
< 0.001) were higher than that of female (AAPC = 7.03%, AAPC
ASMR
=3.09%,
P
< 0.001). The PD standardized mortality rates of urban (AAPC = 5.13%, AAPC
ASMR
=1.76%,
P
< 0.001) and rural (AAPC = 8.40%, AAPC
ASMR
=4.29%,
P
< 0.001) residents both increased gradually. In the age analysis, the mortality rate increased with age. And the mortality rates of those aged > 85 years was the highest. Considering gender, female aged > 85 years had the fastest mortality trend (annual percentage change [APC] = 5.69%,
P
< 0.001). Considering urban/rural, rural aged 80–84 years had the fastest mortality trend (APC = 6.68%,
P
< 0.001).
Conclusions
The mortality rate of PD among Chinese residents increased from 2004 to 2021. Male sex, urban residence and age > 85 years were risk factors for PD-related death and should be the primary focus for PD prevention.
