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A newly identified tick-borne Borrelia species and relapsing fever in Tanzania
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A newly identified tick-borne Borrelia species and relapsing fever in Tanzania
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Journal Article
A newly identified tick-borne Borrelia species and relapsing fever in Tanzania
2003
Overview
Tick-borne relapsing fever caused by the spirochaete Borrelia duttonii is a common cause of serious illness in central Tanzania. Screening of Ornithodoros sp ticks from infested houses for the presence of B duttonii had detected a previously unidentified species of Borrelia. We investigated whether this species infected the human population in a central Tanzanian village, by use of blood slide examination and PCR. PCR was twice as sensitive in detection of infections, showing Borrelia sp in six (11%) of 54 children with fever, and in 13 (4%) of 307 otherwise healthy children. Genotyping Borrelia from 17 infections identified Borrelia duttonii and an unnamed species. Our findings show that the newly discovered species is a causal agent of tick-borne relapsing fever.
Publisher
Elsevier Ltd,Lancet,Elsevier Limited
Subject
/ Bacteria
/ Biological and medical sciences
/ Borrelia
/ Borrelia - isolation & purification
/ Borrelia burgdorferi Group - classification
/ Borrelia burgdorferi Group - isolation & purification
/ Children
/ Fever
/ Humans
/ Malaria
/ Relapsing Fever - epidemiology
/ Relapsing Fever - microbiology
/ Species
/ Ticks
/ Towns
