Asset Details
Do you wish to reserve the book?
Longitudinal evaluation of fecal microbiota transplantation for ameliorating calf diarrhea and improving growth performance
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Longitudinal evaluation of fecal microbiota transplantation for ameliorating calf diarrhea and improving growth performance
Do you wish to request the book?
Longitudinal evaluation of fecal microbiota transplantation for ameliorating calf diarrhea and improving growth performance
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Longitudinal evaluation of fecal microbiota transplantation for ameliorating calf diarrhea and improving growth performance
2021
Overview
Calf diarrhea is associated with enteric infections, and also provokes the overuse of antibiotics. Therefore, proper treatment of diarrhea represents a therapeutic challenge in livestock production and public health concerns. Here, we describe the ability of a fecal microbiota transplantation (FMT), to ameliorate diarrhea and restore gut microbial composition in 57 growing calves. We conduct multi-omics analysis of 450 longitudinally collected fecal samples and find that FMT-induced alterations in the gut microbiota (an increase in the family
Porphyromonadaceae
) and metabolomic profile (a reduction in fecal amino acid concentration) strongly correlate with the remission of diarrhea. During the continuous follow-up study over 24 months, we find that FMT improves the growth performance of the cattle. This first FMT trial in ruminants suggest that FMT is capable of ameliorating diarrhea in pre-weaning calves with alterations in their gut microbiota, and that FMT may have a potential role in the improvement of growth performance.
Here, the authors report the results of a longitudinal multi-omics trial of the use of fecal microbiota transplantation (FMT) to ameliorate diarrhea and restore gut microbial composition in 57 growing calves, and find that oral FMT induces alterations in the gut microbiota correlate with the remission of diarrhea and improves the growth performance of the cattle.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
/ 38/77
/ 82/58
/ Animals
/ Bacteroidaceae - isolation & purification
/ Calves
/ Cattle
/ Cattle - growth & development
/ Cattle Diseases - metabolism
/ Cattle Diseases - microbiology
/ Diarrhea
/ DNA, Bacterial - isolation & purification
/ Fecal Microbiota Transplantation - veterinary
/ Feces
/ Female
/ Gastrointestinal Microbiome - genetics
/ Genomics
/ Humanities and Social Sciences
/ Male
/ RNA, Ribosomal, 16S - genetics
/ Science
/ Weaning
