Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

Efficacy and nephrotoxicity of polymyxin B in elderly patients with carbapenem resistant bacterial infection

by Feng, D. D. , Lei, S. , Jiang, R. L. , Xu, X. , Xia, G. L. , Wang, X. , You, X. B.

in Acute kidney injury / Aged patients / Analysis / Antibiotics / Bacteria / Bacterial diseases / Bacterial infections / Biochemistry / Biomedical and Life Sciences / Biomedicine / Carbapenem-resistant organism / Carbapenems / Care and treatment / Chronic kidney failure / Complications and side effects / CRE bacteria / Creatinine / Drug dosages / Drug Resistance / Drug resistance in microorganisms / Drug therapy / Effectiveness / Elderly / Hospitals / Infection / Infections / Infectious Diseases / Kidney diseases / Medical ethics / Medical Microbiology / Medical prognosis / Medical research / Medicine, Experimental / Microbial Genetics and Genomics / Microbiology / Mortality / Older people / Parasitology / Patients / Polymyxin B / Prevention / Prognosis / Recovery / Regression analysis / Renal insufficiency / Risk factors / Sepsis

2023

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

Efficacy and nephrotoxicity of polymyxin B in elderly patients with carbapenem resistant bacterial infection

by Feng, D. D. , Lei, S. , Jiang, R. L. , Xu, X. , Xia, G. L. , Wang, X. , You, X. B.

2023

Confirm

Do you wish to request the book?

Efficacy and nephrotoxicity of polymyxin B in elderly patients with carbapenem resistant bacterial infection

by Feng, D. D. , Lei, S. , Jiang, R. L. , Xu, X. , Xia, G. L. , Wang, X. , You, X. B.

2023

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

Efficacy and nephrotoxicity of polymyxin B in elderly patients with carbapenem resistant bacterial infection

Feng, D. D.,

Lei, S.,

Jiang, R. L.,

Xu, X.,

Xia, G. L.,

Wang, X.,

You, X. B.

2023

Overview

Background To study the efficacy and nephrotoxicity of polymyxin B in the treatment of elderly patients with carbapenem-resistant organism (CRO) infection. Methods The clinical and microbiological data of patients with CRO-infected sepsis treated with polymyxin B were retrospectively analyzed. The effective rate, bacterial clearance, incidence and recovery rate of acute renal injury (AKI) and prognosis-related indicators in AKI at different stages were compared. Results The effective rate of 215 elderly patients with CRO infection treated with polymyxin was 50.7%. The total bacterial clearance rate was 44.2%, the total incidence of AKI was 37.2%, the recovery rate of AKI was 35%, and the incidence range of polymyxin B-related AKI was 10.2–37.2%. Logistic multivariate regression analysis showed that the predictors of AKI in elderly patients were high APACHE II score, long duration of polymyxin, chronic renal insufficiency and ineffective outcome; the ROC curve showed that the cutoff value for predicting AKI was a serum creatinine concentration of 73 mmol/L before polymyxin B use, and the AUC was 0.931. Conclusions Rational use of polymyxin B is safe and effective in elderly patients with CRO infection, and its effective outcome can improve the recovery rate of AKI.

Share this book

Add to My Shelf

Publisher

BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC

Subject

/ Bacterial infections