Asset Details
Do you wish to reserve the book?
Vaccination and antigenic drift in influenza
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Vaccination and antigenic drift in influenza
Do you wish to request the book?
Vaccination and antigenic drift in influenza
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Vaccination and antigenic drift in influenza
2008
Overview
The relationship between influenza antigenic drift and vaccination lies at the intersection of evolutionary biology and public health, and it must be viewed and analyzed in both contexts simultaneously. In this paper, I review what is known about the effects of antigenic drift on vaccination and the effects of vaccination on antigenic drift, and I suggest some simple ways to detect the presence of antigenic drift in seasonal influenza data. If antigenic drift occurs on the time scale of a single influenza season, it may be associated with the presence of herd immunity at the beginning of the season and may indicate a need to monitor for vaccine updates at the end of the season. The relationship between antigenic drift and vaccination must also be viewed in the context of the global circulation of influenza strains and the seeding of local and regional epidemics. In the data sets I consider – from New Zealand, New York, and France – antigenic drift can be statistically detected during some seasons, and seeding of epidemics appears to be endogenous sometimes and exogenous at other times. Improved detection of short-term antigenic drift and epidemic seeding would significantly benefit influenza monitoring efforts and vaccine selection.
Publisher
Elsevier Ltd,Elsevier Limited
Subject
/ Antigenic Variation - genetics
/ Humans
/ Influenza A Virus, H1N1 Subtype - genetics
/ Influenza A Virus, H1N1 Subtype - pathogenicity
/ Influenza A Virus, H3N2 Subtype - genetics
/ Influenza A Virus, H3N2 Subtype - pathogenicity
/ Influenza Vaccines - administration & dosage
/ Influenza, Human - epidemiology
/ Influenza, Human - immunology
/ Influenza, Human - prevention & control
/ Mutation
/ Seasons
/ Vaccines
/ Viruses
We currently cannot retrieve any items related to this title. Kindly check back at a later time.