Journal Article

Early adoption of triamcinolone acetonide suprachoroidal injection for uveitic macular edema: a physician survey

Naeini, Parisa Emami, Warrow, David J., Raiji, Veena R., Singer, Michael A., Chang, Peter Y., Henry, Christopher R., Chu, David S., Yassine, Mohamed, Shah, Milan, Walter, Scott D., Blinder, Kevin J., Brevetti, Teresa, Rifkin, Lana M., Dacey, Mark S.

2024

Overview

Objective To obtain physicians’ “real-world” perspectives on early experiences with triamcinolone acetonide suprachoroidal injection (SCS-TA) for treatment of patients with uveitic macular edema (UME). Results Twelve retina/uveitis specialists in the United States were surveyed about SCS-TA injection procedure and patient outcomes. Survey participants administered ≥ 291 SCS-TA injections to 243 patients with UME with various disease characteristics (etiologies, chronicity, and anatomical subtypes). Commonly reported reasons for SCS-TA adoption included potential for lowering the risk of steroid-associated intraocular pressure elevations versus intravitreal injections or implants (100%), potential for longer duration of action versus intravitreal steroid injections or implants (92%), and desire to use a new delivery modality (83%). Nearly all participants (92%) found injection procedure relatively easy post-training, with most (75%) procedurally comfortable after completing 2–5 injections. 58% of participants indicated that their patients gained 2–3 lines of vision by first follow-up visit, and 92% reported having patients who experienced 100–150 μm or greater reduction in central subfield thickness. Overall, 92% of participants were satisfied with SCS-TA treatment outcomes. Findings from this survey of early adopters of SCS-TA indicate that the suprachoroidal injection technique was easy to learn and resulted in favorable patient outcomes consistent with clinical trial data.

• Publisher: BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
• Subject: Adult / Aged / Biomedical and Life Sciences / Biomedicine / Care and treatment / Choroid - diagnostic imaging / Choroid - drug effects / Clinical outcomes / Complications and side effects / Corticosteroids / Development and progression / Dropsy / Edema / Eye diseases / Female / Humans / Injection / Injections, Intraocular / Life Sciences / Macular edema / Macular Edema - drug therapy / Male / Medicine/Public Health / Meetings / Middle Aged / Patient outcomes / Patient satisfaction / Patients / Physicians / Research Note / Retina / Steroids / Suprachoroidal injection / Survey / Surveys / Surveys and Questionnaires / Transplants & implants / Treatment / Treatment Outcome / Triamcinolone / Triamcinolone acetonide / Triamcinolone Acetonide - administration & dosage / Triamcinolone Acetonide - therapeutic use / United States / Uveitis / Uveitis - complications / Uveitis - drug therapy / Visual acuity