Asset Details
Do you wish to reserve the book?
Diagnostic value of flow cytometric urine analysis in urinary tract infections of newborns and infants
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Diagnostic value of flow cytometric urine analysis in urinary tract infections of newborns and infants
Do you wish to request the book?
Diagnostic value of flow cytometric urine analysis in urinary tract infections of newborns and infants
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Diagnostic value of flow cytometric urine analysis in urinary tract infections of newborns and infants
2025
Overview
This study aimed to compare the results of flow cytometric urine analysis and urine culture for the rapid diagnosis of urinary tract infections and to determine the leukocyte and bacterial cutoffs that could achieve maximum sensitivity and negative predictive value (NPV) during the newborn and infant periods. This cross-sectional observational study included urine samples submitted for culture from the neonatal intensive care unit and outpatient clinic between April 2019 and December 2021. The urine samples were first inoculated for culture and then analyzed for leukocyte and bacterial counts using a flow cytometric method (Sysmex UF-1000i, Kobe, Japan). Maximum sensitivity and NPV values were determined by examining different bacterial and leukocyte cut-offs with Sysmex UF1000i. A total of 138 urine samples from 103 patients were included in the study. The reasons for urine examinations were prolonged hyperbilirubinemia, sepsis, and insufficient weight gain. Although no association was observed with leukocyte count, a bacterial cut-off of 83.4/µL was identified as the optimal threshold. Diagnostic values, including sensitivity (91.6%), specificity (88.6%), NPV (98.5%), and positive predictive value (PPV) (55%), were satisfactory. Based on current data, we suggest that the Sysmex UF-1000i is a valuable screening tool for detecting UTIs in asymptomatic newborns. Integrating this technology into clinical practice could enhance early diagnosis and treatment, ultimately improving neonatal care outcomes.
Publisher
Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio
Subject
