Asset Details
Do you wish to reserve the book?
Klebsiella-induced infections in domestic species: a case-series study in 697 animals (1997–2019)
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Klebsiella-induced infections in domestic species: a case-series study in 697 animals (1997–2019)
Do you wish to request the book?
Klebsiella-induced infections in domestic species: a case-series study in 697 animals (1997–2019)
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Klebsiella-induced infections in domestic species: a case-series study in 697 animals (1997–2019)
2022
Overview
Klebsiella
species, particularly
K. pneumoniae
, are well-known opportunistic enterobacteria related to complexity of clinical infections in humans and animals, commonly refractory to conventional therapy. The domestic animals may represent a source of the pathogenic and multidrug-resistant
Klebsiella
species to humans. Nevertheless, most studies involving
Klebsiella
-induced infections in domestic animals are restricted to case reports or outbreaks. We retrospectively investigated selected epidemiological data, clinical aspects, and in vitro susceptibility pattern of 697 non-repetitive
Klebsiella
infections in livestock and companion species (1997–2019). The isolates were obtained from different clinical disorders from dogs (
n
= 393), cattle (
n
= 149), horses (
n
= 98), cats (
n
= 27), pigs (
n
= 22), sheep (
n
= 5), goats (
n
= 2), and buffalo (
n
= 1), except four isolates from subclinical bovine mastitis. Urinary (223/697 = 32%), enteric (117/697 = 16.8%), mammary (85/697 = 12.2%), reproductive (85/697 = 12.2%), and respiratory disorders (67/697 = 9.6%) were the most common clinical manifestations. Other miscellaneous clinical pictures (116/697 = 16.6%) included abscesses, otitis, hepatitis, conjunctivitis, pyodermitis, sepsis, and encephalitis. Norfloxacin (183/245 = 74.7%) and gentamicin (226/330 = 68.5%) were the most effective antimicrobials. High in vitro resistance of the isolates was seen to ampicillin (326/355 = 91.8%), amoxicillin/clavulanic acid (25/62 = 40.3%), and trimethoprim/sulfamethoxazole (100/252 = 39.7), and multidrug resistance to ≥ 3 classes of antimicrobials was found in 20.4% (142/697) isolates. Wide variety of clinical manifestations of
Klebsiella
-induced infections was observed, with a predominance of urinary, enteric, mammary, reproductive, and respiratory tract disorders, reinforcing opportunistic behavior of agent. Poor in vitro efficacy was observed to some conventional antimicrobials and ~ 20% of isolates exhibited resistance pattern, reinforcing the need for proper use of drugs on therapy approaches in domestic animals to avoid multidrug-resistant bacteria, an emergent global concern.
Publisher
Springer International Publishing,Springer Nature B.V
Subject
/ Animals
/ Anti-Bacterial Agents - pharmacology
/ Anti-Bacterial Agents - therapeutic use
/ Biomedical and Life Sciences
/ Cats
/ Cattle
/ Diarrhea
/ Dogs
/ Drug Resistance, Multiple, Bacterial
/ Female
/ Fistula
/ Food contamination & poisoning
/ Goats
/ Horses
/ Klebsiella Infections - drug therapy
/ Klebsiella Infections - epidemiology
/ Klebsiella Infections - veterinary
/ Mastitis
/ Microbial Genetics and Genomics
/ Milk
/ Multidrug resistant organisms
/ Mycology
/ Otitis
/ Sepsis
/ Sheep
/ Species
/ Swine
