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Vitamin D supplementation and outcomes in coronavirus disease 2019 (COVID-19) patients from the outbreak area of Lombardy, Italy
by
Barichella, Michela
, Lobascio, Federica
, Zecchinelli, Anna Lena
, Cereda, Emanuele
, Bogliolo, Laura
, Pezzoli, Gianni
, Caccialanza, Riccardo
in
Aged
/ Aged, 80 and over
/ Applied Nutritional Investigation
/ Bias
/ Binding sites
/ Calciferol
/ Caregivers
/ Clinical trials
/ Coronavirus (SARS-CoV-2)
/ Coronaviruses
/ COVID-19
/ COVID-19 - blood
/ COVID-19 - drug therapy
/ COVID-19 - mortality
/ COVID-19 - therapy
/ Dietary Supplements
/ Disease Outbreaks
/ Female
/ Hospitalization
/ Humans
/ Infections
/ Informed consent
/ Italy
/ Male
/ Metabolism
/ Middle Aged
/ Mortality
/ Nutritional Status
/ Outbreaks
/ Outcome
/ Parkinson's disease
/ Prevention
/ Prognosis
/ Prospective Studies
/ Proteins
/ Respiratory distress syndrome
/ Respiratory tract
/ Risk analysis
/ Risk factors
/ SARS-CoV-2
/ Severe acute respiratory syndrome coronavirus 2
/ Subgroups
/ Treatment Outcome
/ Viral diseases
/ Viral infections
/ Vitamin D
/ Vitamin D - analogs & derivatives
/ Vitamin D - blood
/ Vitamin D - therapeutic use
/ Vitamin D Deficiency - blood
/ Vitamin D Deficiency - mortality
/ Vitamin D Deficiency - virology
2021
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Vitamin D supplementation and outcomes in coronavirus disease 2019 (COVID-19) patients from the outbreak area of Lombardy, Italy
by
Barichella, Michela
, Lobascio, Federica
, Zecchinelli, Anna Lena
, Cereda, Emanuele
, Bogliolo, Laura
, Pezzoli, Gianni
, Caccialanza, Riccardo
in
Aged
/ Aged, 80 and over
/ Applied Nutritional Investigation
/ Bias
/ Binding sites
/ Calciferol
/ Caregivers
/ Clinical trials
/ Coronavirus (SARS-CoV-2)
/ Coronaviruses
/ COVID-19
/ COVID-19 - blood
/ COVID-19 - drug therapy
/ COVID-19 - mortality
/ COVID-19 - therapy
/ Dietary Supplements
/ Disease Outbreaks
/ Female
/ Hospitalization
/ Humans
/ Infections
/ Informed consent
/ Italy
/ Male
/ Metabolism
/ Middle Aged
/ Mortality
/ Nutritional Status
/ Outbreaks
/ Outcome
/ Parkinson's disease
/ Prevention
/ Prognosis
/ Prospective Studies
/ Proteins
/ Respiratory distress syndrome
/ Respiratory tract
/ Risk analysis
/ Risk factors
/ SARS-CoV-2
/ Severe acute respiratory syndrome coronavirus 2
/ Subgroups
/ Treatment Outcome
/ Viral diseases
/ Viral infections
/ Vitamin D
/ Vitamin D - analogs & derivatives
/ Vitamin D - blood
/ Vitamin D - therapeutic use
/ Vitamin D Deficiency - blood
/ Vitamin D Deficiency - mortality
/ Vitamin D Deficiency - virology
2021
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Vitamin D supplementation and outcomes in coronavirus disease 2019 (COVID-19) patients from the outbreak area of Lombardy, Italy
by
Barichella, Michela
, Lobascio, Federica
, Zecchinelli, Anna Lena
, Cereda, Emanuele
, Bogliolo, Laura
, Pezzoli, Gianni
, Caccialanza, Riccardo
in
Aged
/ Aged, 80 and over
/ Applied Nutritional Investigation
/ Bias
/ Binding sites
/ Calciferol
/ Caregivers
/ Clinical trials
/ Coronavirus (SARS-CoV-2)
/ Coronaviruses
/ COVID-19
/ COVID-19 - blood
/ COVID-19 - drug therapy
/ COVID-19 - mortality
/ COVID-19 - therapy
/ Dietary Supplements
/ Disease Outbreaks
/ Female
/ Hospitalization
/ Humans
/ Infections
/ Informed consent
/ Italy
/ Male
/ Metabolism
/ Middle Aged
/ Mortality
/ Nutritional Status
/ Outbreaks
/ Outcome
/ Parkinson's disease
/ Prevention
/ Prognosis
/ Prospective Studies
/ Proteins
/ Respiratory distress syndrome
/ Respiratory tract
/ Risk analysis
/ Risk factors
/ SARS-CoV-2
/ Severe acute respiratory syndrome coronavirus 2
/ Subgroups
/ Treatment Outcome
/ Viral diseases
/ Viral infections
/ Vitamin D
/ Vitamin D - analogs & derivatives
/ Vitamin D - blood
/ Vitamin D - therapeutic use
/ Vitamin D Deficiency - blood
/ Vitamin D Deficiency - mortality
/ Vitamin D Deficiency - virology
2021
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Vitamin D supplementation and outcomes in coronavirus disease 2019 (COVID-19) patients from the outbreak area of Lombardy, Italy
Journal Article
Vitamin D supplementation and outcomes in coronavirus disease 2019 (COVID-19) patients from the outbreak area of Lombardy, Italy
2021
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Overview
•Vitamin D has antiinflammatory and immunoregulatory functions.•The involvement of vitamin D in the pathophysiology of coronavirus disease 2019 (COVID-19) is still not clear.•Some studies support a link between vitamin D deficiency and worse COVID-19 outcomes.•Vitamin D may also enhance macrophage activation and aberrant immune response.•In our study, vitamin D supplementation was associated with a trend toward higher mortality.•Supplementation trials are crucial to clarify the role of vitamin D in COVID-19.
Publisher
Elsevier Inc,Elsevier Limited
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