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Deciphering the enigma of Lassa virus transmission dynamics and strategies for effective epidemic control through awareness campaigns and rodenticides

by Awan, Aziz Ullah , Ozair, Muhammad , Hussain, Takasar , Niazai, Shafiullah , Gepreel, Khaled A. , Hamam, Haneen , Ramzan, Yasir

in 639/705/1041 / 639/705/1042 / Basic Reproduction Number / Disease control / Empirical data / Epidemics / Epidemics - prevention & control / Fatalities / Female / Females / Fever / Gender / Growth models / Humanities and Social Sciences / Humans / Infections / Lassa fever / Lassa Fever - epidemiology / Lassa Fever - prevention & control / Lassa Fever - transmission / Lassa virus / Lassa virus - physiology / Male / Mathematical application / Mathematical models / Mathematics / Models, Theoretical / Mortality / multidisciplinary / Neurological disabilities / Optimal control / Population / Rodenticides / Rodents / Science / Science (multidisciplinary) / Sensitivity analysis / Viruses

2024

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Deciphering the enigma of Lassa virus transmission dynamics and strategies for effective epidemic control through awareness campaigns and rodenticides

by Awan, Aziz Ullah , Ozair, Muhammad , Hussain, Takasar , Niazai, Shafiullah , Gepreel, Khaled A. , Hamam, Haneen , Ramzan, Yasir

2024

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Deciphering the enigma of Lassa virus transmission dynamics and strategies for effective epidemic control through awareness campaigns and rodenticides

by Awan, Aziz Ullah , Ozair, Muhammad , Hussain, Takasar , Niazai, Shafiullah , Gepreel, Khaled A. , Hamam, Haneen , Ramzan, Yasir

2024

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Journal Article

Deciphering the enigma of Lassa virus transmission dynamics and strategies for effective epidemic control through awareness campaigns and rodenticides

Awan, Aziz Ullah,

Ozair, Muhammad,

Hussain, Takasar,

Niazai, Shafiullah,

Gepreel, Khaled A.,

Hamam, Haneen,

Ramzan, Yasir

2024

Overview

This study aims to formulate a mathematical framework to examine how the Lassa virus spreads in humans of opposite genders. The stability of the model is analyzed at an equilibrium point in the absence of the Lassa fever. The model’s effectiveness is evaluated using real-life data, and all the parameters needed to determine the basic reproduction number are estimated. Sensitivity analysis is performed to pinpoint the crucial parameters significantly influencing the spread of the infection. The interaction between threshold parameters and the basic reproduction number is simulated. Control theory is employed to devise and evaluate strategies, such as awareness campaigns, advocating condom usage, and deploying rodenticides to reduce the possibility of virus transmission efficiently.

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Publisher

Nature Publishing Group UK,Nature Publishing Group,Nature Portfolio

Subject

639/705/1041

/ 639/705/1042

/ Basic Reproduction Number

/ Disease control

/ Empirical data

/ Epidemics

/ Epidemics - prevention & control