Asset Details
Do you wish to reserve the book?
Uninvited guests: diversity and specificity of Trypanosoma infections in frog-biting midges (Corethrella spp.)
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Uninvited guests: diversity and specificity of Trypanosoma infections in frog-biting midges (Corethrella spp.)
Do you wish to request the book?
Uninvited guests: diversity and specificity of Trypanosoma infections in frog-biting midges (Corethrella spp.)
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Uninvited guests: diversity and specificity of Trypanosoma infections in frog-biting midges (Corethrella spp.)
2025
Overview
Background
Female frog-biting midges (
Corethrella
) are hematophagous micropredators that feed on frogs and serve as vectors for trypanosomes (
Trypanosoma
), unicellular flagellate parasites. Little is known about the infection ecology and host specialization within this tritrophic interaction.
Methods
In this study, we explore the prevalence, diversity and specificity of
Trypanosoma
infections in
Corethrella
across various localities in tropical America and Borneo by sequencing both midge and trypanosome markers in midge samples.
Results
Bayesian phylogenetic analyses and ASAP species delimitation of
Corethrella
(cytochrome c oxidase I [COI]) and
Trypanosoma
(18S, glyceraldehyde 3-phosphate dehydrogenase [GAPDH]) revealed a previously unknown high diversity of frog-biting midge-associated trypanosomes. Across regions and localities, the infection prevalence in midges caught by acoustic midge traps ranged from 2.9% to 23.5%, suggesting that a notable proportion of midges carried trypanosomes, likely acquired from a previous blood meal. At one locality, La Gamba (Costa Rica), the infection prevalence in trap-caught midges was 10.9%, while it was even higher in midges collected directly from frog hosts (20.7%), in agreement with the hypothesis that midges ingest trypanosomes from infected frogs. Bipartite network analyses revealed high degrees of specialization of
Trypanosoma
in trap-caught
Corethrella,
both across all localities (H2′ = 0.87) and when analyzed for our most sampled locality (Cahuita, Costa Rica) alone (H2′ = 0.94).
Conclusions
Our data suggest that most trypanosomes detected in trap-caught midges are established, host-competent (i.e., specialist) parasites in an infective stadium.
Graphical Abstract
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Animals
/ Biomedical and Life Sciences
/ Biting
/ Borneo
/ Diptera
/ ecology
/ Female
/ Females
/ Frogs
/ Glyceraldehyde-3-phosphate dehydrogenase
/ Identification and classification
/ Insect Vectors - parasitology
/ midges
/ Protozoa
/ species
/ Trypanosoma - classification
/ Trypanosoma - isolation & purification
/ Trypanosomiasis - epidemiology
/ Trypanosomiasis - parasitology
/ Trypanosomiasis - transmission
/ Trypanosomiasis - veterinary
/ Vectors
/ Veterinary Medicine/Veterinary Science
/ Virology
