Journal Article

Prevalence of Dementia and Subtypes in Valladolid, Northwestern Spain: The DEMINVALL Study

Fernández-Malvido, Beatriz, San José-Gallegos, Antonio, Iglesias-Rodríguez, Vanessa, Botrán-Velicia, Ana, González-Touya, Marta, Garea, María José, Ortega-Valín, Fernando, Yugueros, María Isabel, Cerón-Fernández, Ana, Tola-Arribas, Miguel Angel, Díaz-Gómez, Bárbara

2013

Overview

To describe the prevalence of dementia and subtypes in a general elderly population in northwestern Spain and to analyze the influence of socio-demographic factors. Cross-sectional, two-phase, door-to-door, population-based study. A total of 870 individuals from a rural region and 2,119 individuals from an urban region of Valladolid, Spain, were involved. The seven-minute screen neurocognitive battery was used in the screening phase. A control group was included. A total of 2,170 individuals aged 65 to 104 years (57% women) were assessed. There were 184 subjects diagnosed with dementia. The crude prevalence was 8.5% (95% CI: 7.3-9.7). Age- and sex-adjusted prevalence was 5.5 (95% CI: 4.5-6.5). Main subtypes of dementia were: Alzheimer's disease (AD) 77.7%, Lewy Body disease, 7.6% and vascular dementia (VD) 5.9%. Crude prevalences were 6.6% (AD), 0.6% (Lewy Body disease), and 0.5% (VD). Dementia was associated with age (OR 1.14 for 1-year increase in age), female sex (OR 1.79) and the absence of formal education (OR 2.53 compared to subjects with primary education or more). The prevalence of dementia in the study population was lower than the most recent estimates for Western Europe. There was a high proportion of AD among all dementia cases and very low prevalence of VD. Old age, female sex, and low education level were independent risk factors for dementia and AD.

• Publisher: Public Library of Science,Public Library of Science (PLoS)
• Subject: Age / Aged / Aged, 80 and over / Alzheimer Disease - epidemiology / Alzheimer's disease / Batteries / Cardiovascular disease / Cognition / Cognitive ability / Collaboration / Dementia / Dementia - epidemiology / Dementia disorders / Demographics / Education / Epidemiology / Female / Females / Geriatrics / Health aspects / Hospitals / Humans / Lewy bodies / Lewy body disease / Male / Middle Aged / Neurodegenerative diseases / Neurology / Older people / Population / Population studies / Prevalence / Primary care / Risk analysis / Risk factors / Rural areas / Sex / Sexually transmitted diseases / Socioeconomic Factors / Spain - epidemiology / STD / Studies / Systematic review / Urban areas / Vascular dementia